Sometimes. . . Sometimes. . . Sometimes. . . Witnessing Urban Placemaking from the Immanence of “the Middle”

Infectious Agents and Autophagy: Sometimes You Win, Sometimes You Lose

The Truth Is Sometimes Simple

Note: The following version of this paper does not contain the proofs of the stated theorems. A longer version, complete with proofs, is forthcoming. §1. Introduction. In "The truth is never simple" (1986) and its addendum (1988), Burgess conducts a breathtakingly comprehensive survey of the complexity of the set of truths which arise when you add a truth predicate to arithmetic, and interpret ...

The Ubiquitin Proteasome System in Neurodegenerative Diseases Sometimes the Chicken, Sometimes the Egg

The ubiquitin-proteasome system targets numerous cellular proteins for degradation. In addition, modifications by ubiquitin-like proteins as well as proteins containing ubiquitin-interacting and -associated motifs modulate many others. This tightly controlled process involves multiple specific and general enzymes of the system as well as many modifying and ancillary proteins. Thus, it is not su...

Sometimes, more is better.

(See the article by El Sahly et al, on pages 703–12.) Influenza causes significant morbidity and mortality with an estimated 36 000 attributable deaths in the United States annually [1]. Human immunodefi-ciency virus (HIV) infection, specifically , advanced disease (CD4 count ,200 cells/lL), has been associated with excess morbidity and mortality [2]. With the use of combination antiretroviral ...

Sometimes size does matter

10.1083/jcb/1722iti3jcb1722iti3Sometimes size does matter D uring myofi broblast differentiation in vitro, “supermature” focal adhesions (FAs) arise due to increased physical stress, report Goffi n et al. (page 259). Additionally, increased tension induces accumulation of αsmooth muscle actin (α-SMA) in stress fi bers that are anchored at these FAs. In vivo, the extracellu...